Evaluation of risk factors for central venous line-associated bloodstrem infections (CLABSIs) and the benefits of central line bundle application in reducing CLABSIs

Authors : Secil DENİZ, İrem AKIN ŞEN, Kevser OZDEMİR, Nurefşan AYDENİZ, Ayşe KIVRAK, Simay SERİN, Hülya SUNGURTEKİN, Hüseyin TURGUT

Pages : 716-725

Doi:10.31362/patd.1343916

View : 25 | Download : 38

Publication Date : 2023-10-01

Article Type : Research Paper

Abstract :Purpose: We aimed to identify the risk factors for central line-associated bloodstrem infections insert ignore into journalissuearticles values(CLABSIs); and the efficacy of chlorhexidine and bundle application to prevent CLABSIs. Materials and methods: This study was performed in the anesthesia-intensive care unit insert ignore into journalissuearticles values(AICU); of a tertiary hospital. A structured survey form including patients’ characteristics and a central line bundle checklist was used for following of patients. Adult patients a.who had undergone recent central venous catheter insert ignore into journalissuearticles values(CVC); insertion at the AICU, and bthose who had been transferred to ICU with the previous catheter insertion in other departments and c.who had received a diagnosis of CLABSI fourty-eight hours after remaining in the ICU were included in the study. The data obtained were evaluated with respect to the risk factors for CLABSIs. Result: The current study included 156 patients with the mean age 67.97±17.20 years insert ignore into journalissuearticles values(median 71.00 years); 66 women insert ignore into journalissuearticles values(42,3%);. Fourty-seven patients developed CLABSIs. Evaluating the results of univariate analysis, the rate of infection was lowest when catheters were inserted with the aim hemodialysis insert ignore into journalissuearticles values(p<0.01);. The subclavian vein insert ignore into journalissuearticles values(p<0.01); and three-lumen catheters insert ignore into journalissuearticles values(p<0.01);, receiving CVCs under emergency condition insert ignore into journalissuearticles values(p=0.04);, having been intubated insert ignore into journalissuearticles values(p=0.01);, undergoing surgery insert ignore into journalissuearticles values(p=0,04); and receiving antibiotics before catheterisation insert ignore into journalissuearticles values(p<0.01);, receiving blood product through CVCs insert ignore into journalissuearticles values(p=0.01);, repeat catheter insertions insert ignore into journalissuearticles values(p<0.01); were found that associated with development of CLABSI. Conclusion: In summary, multivariate analyses showed that repeat catheter insertions insert ignore into journalissuearticles values(p<0.01); and prolonged ICU stay insert ignore into journalissuearticles values(p<0.01); could raise the risk of CLABSIs. However, patients with bundle application had a lover rate of infection insert ignore into journalissuearticles values(p<0.01); was seen.
Keywords : bundle, santral kateter, kan dolaşım enfeksiyonu, yoğun bakım