Can emergency department blood parameters predict coronary artery occlusion in acute myocardial infarction?

Authors : Hülya Yılmaz Başer, Alkame Akgümüş, Ahmet Balun

Pages : 478-485

Doi:10.31362/patd.1423299

View : 40 | Download : 80

Publication Date : 2024-07-05

Article Type : Research Paper

Abstract :Purpose: The aim of this study is to assess the detectability of coronary artery stenosis in patients evaluated for acute myocardial infarction (AMI) in the emergency department and undergoing coronary angiography, based on blood parameters examined in the emergency setting. Materials and methods: In our single-center prospective observational study, patients diagnosed with AMI in the Emergency Department between September 1 and October 31, 2023, and those who underwent coronary angiography by a single cardiologist were included. The blood parameters applied during routine assessment in the Emergency Department were recorded, and parameters with predictive effects based on the percentages of vessel stenosis after angiography were evaluated. Results: A total of 64 patients (44 males and 20 females) who met the study criteria were included in our research. Following the evaluation based on the highest percentage of stenosis in any coronary artery after coronary angiography, patients were divided into two groups. Group 1 consisted of 15 patients with mild stenosis (stenosis <50%), and Group 2 comprised 49 patients with severe stenosis (70-99% stenosis). Group 2, a predominance of male gender was observed along with elevated Troponin-I (Tn-I) levels, and lower values of lymphocyte and platelet counts (p=0.010, p=0.004, p=0.042, and p=0.007, respectively). Conclusion: In males, it has been observed that Tn-I levels are higher in association with coronary stenosis. Alongside atherosclerosis and thrombosis, inflammation may contribute to decreased platelet and lymphocyte counts in cases of severe stenosis. Further prospective, randomized controlled studies with larger sample sizes are needed to confirm these findings.
Keywords : Akut miyokard infarktüsü, kardiyak belirteçler, tam kan sayımı, koroner darlık, koroner anjiografi