Assessment of wound cultures in an oncology hospital

Authors : Ferzan Arslan, Esra Tavukcu, Buket Demirhan, İpek Mumcuoğlu, Turgay Ulaş, Serap Suzuk, Ayşe Semra Güreser, Nese Inan, Gülşen İskender, Tuba Dal

Pages : 654-663

Doi:10.31362/patd.1424237

View : 114 | Download : 179

Publication Date : 2024-10-09

Article Type : Research Paper

Abstract :Purpose: The aim of this study is to evaluate the patient\'s demographic, clinical and laboratory data to determine whether the bacteria isolated from wound cultures are causative agents or colonization, and to determine their antimicrobial susceptibilities. This study aims to assess the demographic, clinical, and laboratory data of patients to distinguish between pathogenic bacteria and colonization in wound cultures, while also determining their antimicrobial susceptibilities. Materials and methods: This retrospective research was conducted in Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital between January 1, 2021 and December 31, 2022. Two hundred thirty six isolates from 186 patients wound cultures were included in the study. Demographic data, clinical data and laboratory results of the patients were evaluated. The isolated bacteria and their antimicrobial susceptibilities were determined. The Q score system was used to evaluate the microbiological quality of wound samples. Results: One hundred fifty nine cases (85%) were inpatients. Totally 119 (63.9%) patients were diagnosed with infection. The Q score for 136 samples (85.5%) was assessed as Q3. The most common isolated microorganisms were coagulase negative-staphylococci (CoNS) (19%), Escherichia coli (14.8%), and Staphylococcus aureus (13.1%), respectively in wound bacterial cultures. The methicillin resistance rate was 55.5% in CoNS and 54.1% in Staphylococcus aureus. Gram-negative bacteria were isolated in 81 (59.9%) infected patients. Among patients with infected wounds, 39 (32.7%) patients had surgical site infections, 25 (21%) prosthesis infections, and diabetic foot infections 3 (2.5%). Infection rates were statistically significantly higher in patients with surgery, prosthesis, and diabetic foot (p=0.054). Conclusion: The Q score serves as a strong indicator for identifying the causative agent in wound infection and distinguishing it from colonization, thus aiding in the prevention of unnecessary antibiotic use. Regular review of local antibiotic susceptibility data is crucial in the clinical treatment of specific patient groups with oncological conditions.
Keywords : Yara kültürü, Q skoru, onkoloji hastaları, antimikrobiyal duyarlılık