COVID 19 IN PREGNANT WOMEN - A RETROSPECTIVE COHORT STUDY

Authors : Kazibe KOYUNCU, Yasemin ALAN, Önder SAKİN, Burçin KARAMUSTAFAOĞLU BALCI, Ramazan DENİZLİ, Ali Doğukan ANĞIN, Abdülmecit ÖKTEM

Pages : 181-186

Doi:10.47115/jshs.793218

View : 20 | Download : 10

Publication Date : 2021-05-28

Article Type : Research Paper

Abstract :Aim: Our aim is to summarize the clinical signs, symptoms, treatment andprognosis of pregnant women with COVID-19 comparing with non pregnant women with COVID-19 at similar age interval. Method: A retrospective study was conducted by reviewing the medical records of all symptomatic pregnant women infected with COVID-19 between March 15 and May 31, 2020. Pregnant women insert ignore into journalissuearticles values(n=21); who applied to tertiary hospital during the same time period and with covid-19 diagnosis formed our working group, and control group insert ignore into journalissuearticles values(n=90); consisted of women who were symptomatic of reproductive age and not pregnant. Seven pregnant women and fifteen non pregnant women were excluded due to being asymptomathic and SARS- CoV-2 positive. COVID-19 infection was diagnosed with computed tomography insert ignore into journalissuearticles values(CT); scans. For laboratory confirmation with PCR, patients were asked to give nasopharyngeal swab samples and tested for SARS-CoV-2 with the blood-based immunoassay kit launchedprovided by Bio-Rad Laboratories. Results: Between March 15 to May 31, 2020, there were 21 pregnant women and 90 non-pregnant women who have confirmed infection for COVID-19. Seven pregnant women and 15 non-pregnant women were SARS-CoV-2 positive and asymptomatic; they are not included in the study. Fourteen pregnant women and 75 non-pregnant women are included in the study. There were no statistically significant difference between groups concerning the incidence of the symptoms insert ignore into journalissuearticles values(p> 0.05);. Early stage is characterized by the ground glass opacities insert ignore into journalissuearticles values(GGO);, which is common in Covid-19 disease, located in the peripheral and subpleural area. In what concerns the severity of the clinical course; the need for hospitalization, the length of hospital stay, the need for mechanical ventilation were statistically significantly higher in pregnant group. All the two groups were prescribed Hydroxychloroquine and antivirals at a similar rate but the use of antibiotics and low molecular weight heparin was statistically significantly higher in pregnant group. Conclusion and Suggestions: We found that COVID-19 infection hassimilar clinical characteristics and a similar rate of pneumonia in pregnant women. But more studies are needed in the field to define a definitive outcome.
Keywords : Coronavirus, COVID 19, SARS CoV 2, obstetric management, pregnancy, fever