Determination and Comparison of Bioactive Compounds in Different Parts of Glycyrrhiza Species

Authors : Fahriye Şeyma ÖZCAN, Nihat ÖZCAN, Özlem ÇETİN, Osman SAĞDIÇ

Pages : 335-342

Doi:10.15832/ankutbd.972048

View : 17 | Download : 6

Publication Date : 2023-01-31

Article Type : Research Paper

Abstract :Glycyrrhiza spp., one of the most widely used herbal medicine for centuries in the world, contain a large number of bioactive such as triterpene saponins and flavonoids which are the main constituents and show broad biological activity. The present study aimed to evaluate the phytochemical profile of extracts from different parts insert ignore into journalissuearticles values(roots, stems and leaves); of all wild Glycyrrhiza spp. grown in Turkey and to reveal that other parts besides the roots are a rich source of bioactive compounds with potential use in the pharmaceutical and food industries. For this purpose, extracted bioactive compounds from different parts of five Glycyrrhiza spp. collected in different provinces of Turkey were determined and compared. The microwave-assisted extraction method, which is mentioned as a green technique and requires low solvent and extraction time, was applied. Determination of bioactives was performed using liquid chromatography- electrospray ionisation tandem mass spectrometry insert ignore into journalissuearticles values(LC-ESI-MS/MS);. Among the collected Glycyrrhiza spp.; in leaf parts, the highest glycyrrhizin insert ignore into journalissuearticles values(GL); insert ignore into journalissuearticles values(2.05±0.07 mg g-1); and glycyrrhetinic acid insert ignore into journalissuearticles values(GA); insert ignore into journalissuearticles values(0.107±0.005 mg g-1); contents were found in Glycyrrhiza flavescens ssp. flavescens; the highest carbenoxolone insert ignore into journalissuearticles values(CBX); insert ignore into journalissuearticles values(0.133±0.006 mg g-1); and liquiritin insert ignore into journalissuearticles values(LQ); insert ignore into journalissuearticles values(1.644±0.014mg g-1); contents were in Glycyrrhiza glabra grown in Polatlı. In stem parts, the highest GL insert ignore into journalissuearticles values(2.735±0.04 mg g-1);, CBX insert ignore into journalissuearticles values(0.069±0.004 mg g-1); and LQ insert ignore into journalissuearticles values(0.602±0.010 mg g-1); contents were determined in G. glabra plant growing in Ankara. In root parts, the highest GL insert ignore into journalissuearticles values(14.68±0.09 mg g-1); and LQ insert ignore into journalissuearticles values(9.735±0.046 mg g-1); contents were detected in G. glabra plant growing in Gaziantep while the highest GA insert ignore into journalissuearticles values(0.136±0.005 mg g-1); and CBX insert ignore into journalissuearticles values(0.188±0.067 mg g-1); contents in Glycyrrhiza flavescens ssp. antalyensis. Thus, it was determined which location in Turkey and which parts of Glycyrrhiza spp. that grow wild in Turkey can be used as a priority for the food and pharmaceutical industry with this study.
Keywords : Glycyrrhiza, microwave assisted extraction, bioactive compounds, LC ESI MS MS