Evaluation of Primary and Secondary Raynaud’s Phenomenon in Childhood

Authors : Müge SEZER, Elif ÇELİKEL, Fatma AYDIN, Zahide EKİCİ TEKİN, Tuba KURT, Nilüfer TEKGÖZ, Cüneyt KARAGÖL, Serkan COŞKUN, Melike KAPLAN, Banu ACAR

Pages : 7-12

Doi:10.12956/tchd.1054799

View : 22 | Download : 6

Publication Date : 2023-01-30

Article Type : Research Paper

Abstract :Objective: To evaluate the clinical, laboratory and capillaroscopic findings of pediatric patients with Raynaud’s phenomenon. Material and Methods: Ninety-five pediatric patients who were diagnosed with Raynaud’s phenomenon between January 2014 and January 2021, were retrospectively examined. The demographic data, laboratory parameters and capillaroscopic findings of the patients were recorded. The capillaroscopic findings of the patients were classified as normal, nonspecific abnormalities and scleroderma pattern. Results: Primary Raynaud’s phenomenon was present in 84 insert ignore into journalissuearticles values(88.5%); patients, and secondary Raynaud’s phenomenon was present in 11 insert ignore into journalissuearticles values(11.5%);. Arthralgia, arthritis, rash and recurrent fever were significantly more common in secondary Raynaud’s phenomenon insert ignore into journalissuearticles values(p=0.001, p=<0.001, p=0.01, p=0.035, respectively);. Antinuclear antibody positivity >1/320 was significantly higher in the patients with secondary Raynaud’s phenomenon insert ignore into journalissuearticles values(p=0.01);. Of the 40 patients who had capillaroscopy performed, 2 had a scleroderma pattern, 19 had nonspecific changes, and 19 had normal nailfold capillaroscopic findings. Capillary irregularity, tortuous capillaries and increased branching were significantly higher in the secondary Raynaud’s phenomenon cases insert ignore into journalissuearticles values(p=0.015, p=0.015, p=0.003, respectively);. Conclusion: Having antinuclear antibody titer >1/320 and detection of capillary irregularity, tortuous capillaries and increased branching may be useful in distinguishing primary and secondary Raynaud’s phenomenon. 
Keywords : Antinükleer antikor, kapilleroskopi, pediatri, Raynaud Fenomeni, Romatoloji