Advanced age; not a contraindiction for resections of colorectal liver metastasis recurrence

Authors : Recep Erçin SÖNMEZ

Pages : 160-167

Doi:10.38053/acmj.1257547

View : 11 | Download : 4

Publication Date : 2023-03-27

Article Type : Research Paper

Abstract :Aim: The influence of advanced age on the outcome of repeat resections performed for colorectal liver metastasis insert ignore into journalissuearticles values(CLM); is ill-defined. We aimed to evaluate the safety and efficacy of repeat resections performed for the recurrence of CLMs in younger insert ignore into journalissuearticles values(≤70 years); and elderly patients insert ignore into journalissuearticles values(70< years);, and to define predictive factors of survival. Material and Method: A prospectively maintained database of a single center including 291 CLM patients between 1998 and 2019 was analyzed retrospectively. Short and long-term outcomes were compared among younger insert ignore into journalissuearticles values(n=99, 34%); and elderly insert ignore into journalissuearticles values(n=192, 66%); patient groups who were treated by repeat resections for CLM recurrence. Results: Although statistically not significant, analysis of different age groups insert ignore into journalissuearticles values(≤70, 70-75, 75-80, and 80< years); have given similar results in terms of 1, 3, and 5-year survival insert ignore into journalissuearticles values(p=0.143);. Globally curative resection was validated as a determinant factor in the estimation of survival following resections performed for recurrences according to multivariate analysis insert ignore into journalissuearticles values(p<0.05);. Conclusion: Repeat resections for the recurrence of CLMs in selected elderly patients are reliable with regards to similar survival outcomes achieved compared to their younger counterparts.
Keywords : Colorectal liver metastasis CLM, , liver recurrence, resection, elderly patients