An Investigation of Diabetes Mellitus and Vitamin D Deficiency in Patients Presented to Internal Medicine Outpatient Clinic

Authors : Deniz GEZER, Seval Müzeyyen ECİN

Pages : 25-32

Doi:10.33716/bmedj.1240748

View : 10 | Download : 6

Publication Date : 2023-02-24

Article Type : Research Paper

Abstract :Introduction: Vitamin D deficiency plays a role also in the occurrence of autoimmune diseases, including heart disease, cancer, inflammatory bowel diseases, diabetes, and rheumatological diseases. In addition, vitamin B12 deficiency, one of the autoimmune diseases, can also be seen in cases of Vitamin D deficiency. Furthermore, Vitamin D is also associated with insulin secretion and increased insulin sensitivity in target cells, and relevant studies reported Vitamin D deficiency at the initial stage of diabetes mellitus insert ignore into journalissuearticles values(DM);. Accordingly, the present study aimed to investigate the relationship between Vitamin D, DM, Vitamin B12, and ferritin in patients presented to the internal medicine outpatient clinic. Materials and Methods: The data from adults aged 18 years and over, who presented to the Internal Medicine Outpatient Clinic of the Mersin City Training and Research Hospital between 01 June 2021 and 31 December 2021 were retrospectively investigated. Results: 476 insert ignore into journalissuearticles values(95.2%); patients had vitamin D levels below 30 ng/ml, 20 insert ignore into journalissuearticles values(4.0%); had vitamin B12 levels below 200 pg/ml, and 319 insert ignore into journalissuearticles values(63.8%); patients had ferritin levels below 20 ng/ml. There was a significant decrease in ferritin in female gender insert ignore into journalissuearticles values(p<0.01);, advanced age patients with DM insert ignore into journalissuearticles values(p<0.01);, and patients without DM insert ignore into journalissuearticles values(p=0.01);. Conclusion and Recommendations: Vitamin D deficiency plays an important role in the occurrence of many diseases, including DM and Vitamin B12 deficiency. Ferritin, an inflammatory marker, has been shown to be associated with a number of diseases. As a result of the present study, there was a significant decrease in ferritin in advanced age patients with DM, female sex, and patients without DM, and a higher rate of Vitamin D deficiency. Further long-terms studies including post-treatment follow-up periods are required to diagnose the above diseases in an earlier period, prevent complications, and prevent diseases by means of vitamin deficiency treatments
Keywords : Vitamin D deficiency, Diabetes Mellitus, Ferritin, Vitamin B12