Comparison of the effects of TIVA and inhalation anesthetic techniques on olfactory functions and olfactory memory: a randomized prospective study

Authors : Üstün SEZER, Rahşan Dilek OKYAY, Hilal AYOĞLU, Bengü Gülhan KÖKSAL, Gamze KÜÇÜKOSMAN, Özcan PİŞKİN, Nilay Nur GENÇOĞLU, Ferruh AYOĞLU, Fikret ÇINAR, Işıl ÖZKOÇAK TURAN

Pages : 11-19

Doi:10.17826/cumj.1133058

View : 18 | Download : 11

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :Purpose: This study aimed to investigate the effects of different general anesthesia procedures on postoperative olfactory functions and olfactory memory. Materials and Methods: This prospective study was conducted with 97 patients. Patients were divided into three groups based on anesthesia induction and maintenance technique: Group P insert ignore into journalissuearticles values(induction and maintenance with propofol);, Group PS insert ignore into journalissuearticles values(induction with propofol, maintenance with sevoflurane);, and Group S insert ignore into journalissuearticles values(induction with sevoflurane, maintenance with sevoflurane);. Butanol threshold and olfactory identification tests were administered 30 minutes insert ignore into journalissuearticles values(min); before the operation insert ignore into journalissuearticles values(T1); and 30 min insert ignore into journalissuearticles values(T2);, 8 hours insert ignore into journalissuearticles values(h); insert ignore into journalissuearticles values(T3); and 24 h insert ignore into journalissuearticles values(T4); after the operation. Results: Butanol threshold values were increased at the T2 time point compared to baseline in all groups, which returned to baseline values at T3 only in Group P. There was a significant difference between Group P and Group S in terms of butanol threshold values at all time points except T1. When olfactory identification increased at T3 and T4 compared to baseline in Group P, there was a significant difference between T2, T3, and T4 time points in Group S, and between T2 and T3 time points in Group PS as compared to Group P. Conclusion: Propofol only causes a temporary impairment in olfactory functions in the early period and does not alter olfactory memory.
Keywords : Koku işlevi, Propofol, Sevofluran, Koku hafızası