The relationship between dietary antioxidant capacity and serum oxidative stress index of hemodialysis patients

Authors : Hacer ALATAŞ, Mendane SAKA, Nurgül ARSLAN, Bülent YAPRAK, Önder OTLU, İrem PEMBEGÜL

Pages : 72-83

Doi:10.17826/cumj.1179523

View : 17 | Download : 10

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :Purpose: Oxidative stress increases in uremic conditions such as kidney failure and during hemodialysis. In this study, it was aimed to examine the relationship between the total antioxidant capacity of the diet and the serum oxidative stress insert ignore into journalissuearticles values(sOSI); index in hemodialysis patients. Materials and Methods: In this study conducted with 82 individuals insert ignore into journalissuearticles values(41 patients and 41 controls);. Demographic characteristics and anthropometric measurements of the individuals were taken by researchers. In order to determine the nutritional status of the individuals, 3-day food consumption records were taken and the total antioxidant capacity of the diet was calculated. Results: The mean age of the individuals participating in the study was found to be 54.01±2.24 years. Hemodialysis treatment mean for 4.8±3.12 years. While 41.46% of hemodialysis patients were moderately malnourished. Dietary Oxygen Radical Absorption Capacity insert ignore into journalissuearticles values(dORAC); insert ignore into journalissuearticles values(μmol); measurement result was found to be 2415.3±1073.45, 5468.4±2393.85 in the hemodialysis and control groups, respectively. In the multiple logistic regression analysis performed, the decrease in body mass index insert ignore into journalissuearticles values(OR 2.21 95% CI 1.050-2.317); and triceps skinfold thickness values insert ignore into journalissuearticles values(OR 3.22 95% CI 1.722-4.001); in hemodialysis patients led to an increase in the sOSI value. It has been observed that when dietary protein insert ignore into journalissuearticles values(OR 1.23 95% CI 1.003-3.189);, vitamin C insert ignore into journalissuearticles values(OR 2.88 95% CI 1.004-3.106); and dTAC insert ignore into journalissuearticles values(OR 2.04 95% CI 1.967-2.001); increase, the sOSI value decreases in hemodialysis patients. Conclusion: There is a positive relationship between diet total antioxidant capacity and serum antioxidant level, and it was determined that the dietary antioxidant capacity of hemodialysis patients was significantly lower than that of healthy individuals. According to the results of the study, it is recommended to monitor the food consumption status of hemodialysis patients in order to increase the dietary antioxidant capacity.
Keywords : Kronik böbrek yetmezliği, hemodiyaliz, diyet total antioksidan kapasitesi, serum oksidatif stres indeksi