A neuroimaging study of altered cortical and subcortical volume in adolescent methamphetamine users

Authors : Zekeriya TEMİRCAN

Pages : 1148-1156

Doi:10.17826/cumj.1349328

View : 23 | Download : 38

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Purpose: The aim of this study was is to compare brain structure volume, including cortical and subcortical regions of adolescents- methamphetamine users versus non-users. Materials and Methods: The study was designed to be cross-sectional, and structural magnetic resonance imaging scans were obtained from the participants, including ten methamphetamine users and nine non-users. volBrain program was used to evaluate the images. Results: The results showed that methamphetamine users altered brain structures- temporal, parietal lobes, nucleus accumbens, amygdala, hippocampus, and thalamus volume. Also, the statistically significant difference in the volume between methamphetamine users and non-users was found in subcortical regions except putamen by age. Volumetric analysis of methamphetamine use in adolescents confirms a reduction in temporal lobes insert ignore into journalissuearticles values(methamphetamine users M±SD=3.43±0.18 non-users M±SD=3.48±0.22); and parietal lobes insert ignore into journalissuearticles values(methamphetamine users M±SD=2.23±0.24, non-users M±SD=2.37±0.33); in cortical regions in the brain as tissue volume. However, methamphetamine uses caused an increase in volume in the subcortical regions. Conclusion: Methamphetamine use appears to show decreased volume in the brain regions with age, which has adverse effects on cognitive, emotional, memory, and social abilities.
Keywords : Metamfetamin, Beyin hacmi, Ergen, Kortikal, Subkortikal bölgeler