A MALT LYMPHOMA PRESENTING WITH PRIMARY DIFFUSE RENAL INVOLVEMENT

Authors : Abdulkadir Karismaz, Elif Suyani, Mehmet Hilmi Doğu, Gülben Erdem Huq, Sermin Altindal, Istemi Serin, Osman Yokuş

Pages : 248-250

View : 48 | Download : 101

Publication Date : 2023-10-16

Article Type : Other Papers

Abstract :The involvement of kidney in marginal zone lymphoma (MZL) is not a frequent condition. Seventy-seven year old female presented with renal failure. Renal biopsy revealed diffuse lymphoid infiltration replacing the normal renal tissue. Immunohistochemical staining was CD20, CD38, kappa, IgD positive and CD3, lamda, cyclin D1, CD5, CD23, CD43, lambda negative. Ki-67 was 10% positive. The patient was diagnosed as MALT type MZL. Body 18Fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) performed for staging revealed diffuse FDG uptake in both kidneys and no lymphadenopathy was detected. Bone marrow aspiration and biopsy were normal. Rituximab-bendamustin chemotherpy regimen was started. In conclusion, this is the first case of MALT lymphoma involving kidney diffusely which requires rapid diagnosis and treatment to prevent irreversible loss of renal functions.
Keywords : MALT lenfoma, böbrek, böbrek tutulumu, Lenfoma, Lymphoma, MALT lymphoma, kidney, renal involvement