Investigation of Saliva Parameters and Tissue Factor in Healthy Individuals Who Had Survived COVID-19 Infection

Authors : Şehkar Oktay, Eren Aslan, Gökçe Akyol, Saliha Kaya, Füsun Karatepe

Pages : 55-58

Doi:10.29228/erd.71

View : 70 | Download : 60

Publication Date : 2024-08-29

Article Type : Research Paper

Abstract :Objectives: Oral mucosa is a suitable area for the spread of COVID-19 infection and it causes dysfunction in the salivary glands. Tissue factor is an important regulator that plays a role in hemostasis and coagulation mechanisms, also found in saliva. The aim of the study is to examine the effects of COVID-19 infection on salivary gland function and oral health through saliva. Materials and Methods: The control group consists of 20 individuals who have not had a COVID-19 infection before, while the COVID group consists of 26 individuals who had a COVID-19 infection at least 6 months ago. Salivary flow rate, buffering capacity, pH, and tissue factor activity were evaluated in saliva samples. Results: Salivary flow rate, buffering capacity, and tissue factor activity decreased significantly in the COVID group compared to the controls, while pH was found to be statistically not significant between the groups. Conclusions: Various damages and related dysfunctions develop in the oral tissues following a COVID-19 infection. For this reason, individuals who have had COVID-19 might have more tendency to oral diseases.
Keywords : Tükürük, Akış hızı, Tamponlama kapasitesi, Doku faktörü, COVID 19