Introduction In Vitro Culture Withania Somnifera for Obtain Secondary Metabolites and Further Study

Authors : R.e. PAVLIKOV

Pages : 64-0

Doi:10.21448/ijsm.240731

View : 9 | Download : 5

Publication Date : 2014-07-14

Article Type : Research Paper

Abstract :Ashwagandha is a branching erect shrub height from 30 to 150 cm covered with thick vegetation down insert ignore into journalissuearticles values(tomentosa);. The leaves are oval, up to 10 cm in length and 2-2.5 cm in width.Green or yellow flowers of which then grow red fruit. Ashwagandha roots fleshy, cylindrical, white or light brown in color. Ashwagandha is found in arid parts of India, Asia and Northern Africa.Ashwagandha contains steroidal compounds are of great interest for researchers, is: steroidal lactones ergostanovogo type, in particular vitanolidy A-Y, degidrovitanolid -R, vitasomniferin -A, vitasomidienon, vitasomniferols A-C, vitaferin A, vitanon and etc. In addition, Ashwagandha contains fitosterolysitoindozidy VII - X and beta-sitosterol, alkaloids insert ignore into journalissuearticles values(ashvagandin, kuskohigrin, Tropin, psevdotropin, izopellitierin, anaferin);, a variety of amino acids, including tryptophan, as well as large amounts of iron.Vitanolidy insert ignore into journalissuearticles values(withanolides); - fitosteroidov group representing unsaturated steroidal lactones polioksisteroidy. The first compound of this class - vitaferin A - has been allocated in the 60s. the last century of the Indian plant Withania somnifera insert ignore into journalissuearticles values(fam. Solanaceae);. Currently, there are several rows of this class of compounds insert ignore into journalissuearticles values(somniferin, vitanon);. Used as biologically active food supplements. Found in Physalis have anti-inflammatory, analgesic and anti-cancer effects.Interest steroidal lactone acting opposite ecdysone insert ignore into journalissuearticles values(molting hormones); on insects by inhibiting the molting.Ashwagandha has: antioxidant, toning, anti-aging, antiseptic, blood purifier, anti-viral, anti-inflammatory, immunomodulatory, healing, anabolic properties.An aqueous extract of Ashwagandha root to prevent the development of lipid peroxidation caused deliberately for experimental purposes in rats and mice insert ignore into journalissuearticles values(Dhuley 1998a);. Withania somnifera extract with an equimolar concentration sitoindozidov VII - X and vitaferina A, caused an increase in the level of superoxide dismutase, catalase, glutathione peroxidase and in rat brain insert ignore into journalissuearticles values(Bhattacharyaetal 1997);.
Keywords : Withania somnifera Ashwagandha, , nightshade