Structure-Activity and Antioxidant Properties of Quercetin and Its Co2+ Chelate

Authors : Aslı ÖZTÜRK KİRAZ, Fatih YALÇIN

Pages : 414-424

Doi:10.21448/ijsm.954992

View : 12 | Download : 8

Publication Date : 2021-12-26

Article Type : Research Paper

Abstract :Quercetin and its metal complexes have anti-oxidation, anti-bacterial, anti-tumor, and kinds of enzymatic activities. Studies in recent years, these activities are very important for health and pharmaceutics. The purpose of this manuscript is to determine the structure-activity relations and antioxidant properties of the Quercetin and Quercetin-Co2+ chelate from a theoretical view and to be used these compounds in the treatment of the diseases. We found that Quercetin is more stable than Quercetin-Co2+ chelate but Quercetin-Co2+ chelate is more conductive and the O22-H bond of the Quercetin molecule has the highest antioxidant activity. The remarkable electron delocalization occurred between the donor insert ignore into journalissuearticles values(C17-C19); anti bond and acceptor insert ignore into journalissuearticles values(C13-C15); anti bond with 319.62 kcal/mol stabilization energy in Quercetin.
Keywords : Polyphenol compounds, Metal chelating activity, Electronic properties, Antioxidant activity