Evaluation of Pretreatment Serum Albumin-to-Globulin Ratio in Dogs with Naturally Occurring Parvovirus Infection

Authors : Didem PEKMEZCİ, Kübra ÇAKIR

Pages : 118-124

Doi:10.35229/jaes.690811

View : 14 | Download : 6

Publication Date : 2020-06-30

Article Type : Research Paper

Abstract :A pretreatment albumin insert ignore into journalissuearticles values(ALB);-to-globulin insert ignore into journalissuearticles values(GLB); ratio insert ignore into journalissuearticles values(AGR); with a predictive significance has been used as an indispensable marker among cancer types for recurrence and prognosis in human patients. This study aims to determine whether the pretreatment AGR and total calcium insert ignore into journalissuearticles values(tCa);, magnesium insert ignore into journalissuearticles values(Mg);, ionised phosphorus insert ignore into journalissuearticles values(iP);, total protein insert ignore into journalissuearticles values(TP);, and haematology parameters—as bedside markers—differs in dogs with naturally occurring parvovirus infection insert ignore into journalissuearticles values(PVI);. Fourteen client-owned dogs aged 2-8 months that were naturally infected with parvovirus insert ignore into journalissuearticles values(PV); were enrolled as the study group. Seven client-owned, healthy dogs of the same age formed the control group. Pretreatment mean complete blood counts, serum tCa, Mg, iP, TP, ALB, globulin GLB and AGR values, were compared between groups. The pretreatment mean WBC, NEU, LYM, EOS, GLB, and TP levels were found to be significantly lower insert ignore into journalissuearticles values(P < 0.05); in the study group, when compared to the control group. On the other hand, pretreatment AGR with iP was found to be statistically higher insert ignore into journalissuearticles values(P < 0.05); in the study group, when compared to the control group. There was a significant positive correlation between mean serum GLB and WBC levels in the current study. A significant positive correlation between mean serum TP and WBC levels was also found. This preliminary study demonstrates that pretreatment serum GLB levels and the AGR—as easy, inexpensive, objective, and non-invasive biomarkers—could be the new prognostic marker candidates in dogs with naturally occurring PVI.
Keywords : Albumin to globulin ratio, canine, globulin, parvovirus, prognostic marker candidate