BIOACTIVITIES OF ISOLATED PHYTOCHEMICAL CONSTITUENTS AND EXTRACTS OF Crateva adansonii DC.

Authors : Vinujan SHANMUGALİNGAM, Saravanan VİVEKANANDARAJAH SATHASİVAMPİLLAİ, Pholtan Rajeev SEBASTİAN

Pages : 19-30

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Publication Date : 2021-06-30

Article Type : Review Paper

Abstract :Crateva adansonii DC. is a tree that belongs to the Capparaceae family. In traditional medicine, it is used to cure several disorders including constipation, earache, fevers, itch, malaria, rheumatic pains, and snakebites. Furthermore, phytochemicals including daucosterol, phytol, pyropheophorbide A, suramin, and ψ-taraxasterol have been isolated from different parts of C. adansonii. This review paper objects to scrutinize, recap, and document the reported bioactivity studies of C. adansonii. ScienceDirect, Web of Science, Semantic Scholar, Scopus, and PubMed were utilized to detect the applicable published works from 1900 to June 2021. Up to now, in vivo and in vitro scientific evidence is available for various bioactivities. In addition, analgesic, antiarthritic, antibacterial, anticancer, antifungal, antiinflammatory, antimalarial, antioxidant, and antiprotozoal activities have been observed for various parts of this plant species. Hitherto, only two bioactive compounds have been isolated from C. adansonii. Daucosterol isolated from bark showed anticancer activities and lupeol isolated from leaves showed antioxidant activities. This work supports put a basis for further studies associated with this plant species in the future.
Keywords : Capparaceae, Crateva adansonii, ethnobotany, Siddha Medicine, Sri Lanka