The Evaluation of Testes by Shear Wave Elastography in Patients with Isolated Hypogonadotropic Hypogonadism

Authors : Osman DERE, Hüseyin KARAASLAN

Pages : 729-734

Doi:10.16899/jcm.1330250

View : 54 | Download : 35

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Aim: The aim of this study was to evaluate testicular stiffness by shear wave elastography insert ignore into journalissuearticles values(SWE); in patients with isolated hypogonadotropic hypogonadism insert ignore into journalissuearticles values(IHH); and to compare it with healthy controls. Methods: In this prospective study, 35 patients with IHH insert ignore into journalissuearticles values(group 1); and 40 healthy controls insert ignore into journalissuearticles values(group 2); were evaluated. These two groups were compared in terms of age, testicular volume, and SWE values. In a subsequent analysis, IHH patients were divided into 3 groups: those who were newly diagnosed and did not receive any treatment insert ignore into journalissuearticles values(group A);, those who received testosterone replacement insert ignore into journalissuearticles values(group B);, and those who received human chorionic gonadotrophin alpha insert ignore into journalissuearticles values(hCG); insert ignore into journalissuearticles values(group C);. Testicular volumes and SWE values were also compared between these subgroups. Results: Testicular volumes were significantly lower in group 1 than in group 2 insert ignore into journalissuearticles values(p<.001);. Group 1 had significantly higher testicular SWE values than group 2 insert ignore into journalissuearticles values(p<.001);. There was also a negative correlation between the mean value of testicular stiffness and testicular volume in group 1 insert ignore into journalissuearticles values(r=-0.555, p=.001 for right testes, r=-0.403, p=.016 for left testes);. Results of subsequent analysis by treatment status showed that patients in group C had significantly increased testicular volumes. In addition, they tended to have lower SWE values, when compared to groups A and B. Conclusions: SWE values were significantly higher in IHH patients compared to healthy controls. We found significant improvements in SWE values even in patients receiving short-term hCG replacement. Further research is needed on whether basal SWE values of IHH patients can predict fertility in patients with IHH.
Keywords : izole hipogonadotropik hipogonadizm, elastografi, testiküler sertlik, erkek infertilitesi