Evaluation of Vitamin B12, Folic Acid, Ferritin and Vitamin D Levels in Obsessive Compulsive Disorder

Authors : Okan İMRE, Rahim KOCABAŞ

Pages : 994-998

Doi:10.16899/jcm.1335202

View : 36 | Download : 38

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Aims: Obsessive compulsive disorder insert ignore into journalissuearticles values(OCD); is a heterogeneous disorder characterized by obsessions and compulsions. Despite the studies, etiopathogenesis is not fully understood. Pharmacological and psychosocial interventions in OCD may be insufficient due to limited knowledge of etiopathogenesis. Therefore, it is important to find inexpensive and easily determined biochemical parameters related to etiopathogenesis. In this study, the relationship between OCD and vitamin B12 insert ignore into journalissuearticles values(VitB12);, folic acid insert ignore into journalissuearticles values(FA);, vitamin D insert ignore into journalissuearticles values(VitD); and ferritin was investigated. Material and Method: 50 patients with OCD insert ignore into journalissuearticles values(12 female, 38 male); and 50 healthy controls insert ignore into journalissuearticles values(HC); insert ignore into journalissuearticles values(13 female, 37 male); were included in this retrospective study. Serum VitB12, FA, ferritin and 25-OH VitD levels of both groups were compared. Results: VitB12 insert ignore into journalissuearticles values(p <0.001);, FA insert ignore into journalissuearticles values(p =0.004); and 25-insert ignore into journalissuearticles values(OH);VitD insert ignore into journalissuearticles values(p =0.001); serum levels were significantly lower in the OCD group than in the HC group. There was no significant difference between the two groups in terms of ferritin values. Conclusion: Our study shows that serum VitB12, FA and VitD deficiency can contribute to etiopathogenesis in OCD patients. This study may lead to research to find new pathways related to etiopathogenesis. For this, prospective studies with large participation are needed, including the post-treatment period.
Keywords : Obsesyon, B12 vitamini, folik asit, ferritin ve D vitamini