Arterial Spin Labelling Magnetic Resonance Perfusion Imaging for the Diagnosis of Acute Cerebral Venous Thrombosis

Authors : Ümit GÖRGÜLÜ, Hatice Gül HATİPOĞLU ÇETİN

Pages : 896-900

Doi:10.16899/jcm.1349221

View : 34 | Download : 32

Publication Date : 2023-09-30

Article Type : Research Paper

Abstract :Abstract Background: Early diagnosis of cerebral venous thrombosis insert ignore into journalissuearticles values(CVT); is crucial for a favourable prognosis as CVT can lead to severe outcomes. However, certain scenarios, such as during pregnancy, restrict the use of contrast agents, thus rendering conventional magnetic resonance imaging insert ignore into journalissuearticles values(MRI); methods insufficient for accurate diagnosis. In light of these challenges, our study endeavours to assess the diagnostic potential of the arterial spin labelling magnetic resonance perfusion insert ignore into journalissuearticles values(ASL-MRP); technique, a contrast-agent–free approach, in the context of CVT diagnosis. Materials and Methods: Between 1 March 2022 and 30 May 2022, patients diagnosed with CVT via contrast-enhanced MR venography in the neurology clinic of our hospital were evaluated through ASL-MRP. Patient-specific demographics, including age, gender, presenting symptoms, underlying causes, impacted cortical sinus structures and MRI findings, were documented. Within the framework of ASL-MRP, an elevation in cerebral blood flow insert ignore into journalissuearticles values(CBF); detected within the affected sinus and/or neighbouring structures was deemed indicative of pathological conditions. Results: Among the 13 patients included in our study, six were diagnosed with acute CVT, whereas seven were diagnosed with chronic CVT. The assessment of CBF using ASL-MRP revealed CBF elevation in five out of the six cases insert ignore into journalissuearticles values(83.3%); exhibiting acute CVT. However, no anomalous findings were observed in the ASL-MRP scans of patients presenting with chronic CVT. Discussion: The utilisation of ASL-MRP eliminates the need for contrast agent administration. It is a promising technique in facilitating the diagnosis of acute CVT and distinguishing it from chronic CVT cases.
Keywords : Serebral venöz tromboz, gebelik, tanı, arteriyel spin etiketleme manyetik rezonans perfüzyon görüntüleme