CLINICAL COURSE OF A DEATH FROM RANOLAZINE OVERDOSE: A CASE REPORT

Authors : Mehmet Ali YAVUZ, Ramazan ASOGLU

Pages : 35-38

Doi:10.33706/jemcr.607486

View : 12 | Download : 8

Publication Date : 2020-10-09

Article Type : Other Papers

Abstract :Introduction:  Ranolazine is a new medication for angina pectoris. It is usually used for refractory angina pectoris. Ranolazine overdose may cause some serious effects on heart like other cardiac medications. Case Report:  We report the case of a 21-year-old girl was brought to the emergency department because of an attempt to commit suicide with a large number of Ranolazine tablets. She went into the coma and was unresponsive to verbal and painful stimuli after two hours of admission. There was no pathological findings on brain computed tomography insert ignore into journalissuearticles values(CT); and Magnetic Resonance Imaging insert ignore into journalissuearticles values(MRI);. The QT interval was 420 msec and more extended than previous measurements. The patient had three episodes of polymorphic nonsustained ventricular tachycardia insert ignore into journalissuearticles values(NSVT);. Despite the amiodarone treatment, the NSVT evolved to polymorphic sustained ventricular tachycardia insert ignore into journalissuearticles values(Torsade de Pointes; TdP); and Ventricular fibrillation insert ignore into journalissuearticles values(VF);. The patient underwent CPR and accepted as death end of the resuscitation due to asystole on the ECG. Conclusion:  Ranolazine overdose is known that may cause some serious ECG changes and seizures. But suddenly entering a coma and death has never been reported with ranolazine intoxication in literature.
Keywords : Ranolazine overdose, Death, Torsades De Pointes