Prescribing pattern of antibiotics and guideline adherence in acute community-acquired uncomplicated urinary tract infections in Pakistani women

Authors : Zakir KHAN, Junaid KHAN, Asghar KHAN, Faiz ULLAH KHAN, Sohail KAMRAN, Muhammad Nasir JAMAL, Khayal MUHAMMAD

Pages : 116-120

Doi:10.32322/jhsm.601073

View : 12 | Download : 8

Publication Date : 2019-09-22

Article Type : Research Paper

Abstract :Aim: Acute urinary tract infection is one of the most predominant community-acquired infections. These infections are often treated with antibiotics, but its inappropriate usage leads to Clostridium difficile infections, resistance development and higher cost. To evaluate the prescribing pattern of antibiotic and adherence to Infectious Diseases Society of America insert ignore into journalissuearticles values(IDSA); guidelines in uncomplicated urinary tract infections insert ignore into journalissuearticles values(cystitis and pyelonephritis); among females. Material and Method: A retrospective, chart-review study was conducted in a teaching hospital in Pakistan. Consecutively two hundred insert ignore into journalissuearticles values(n=200; cystitis: n=100, pyelonephritis: n=100); medical charts of female patients kept for the last 1 year insert ignore into journalissuearticles values(May 2018 to April 2019); were enrolled through random systematic sampling technique for comparison purpose. Important information was extracted from medical charts and compared with IDSA recommendations. Finally, collected data were entered into SPSS, version 22.0 for statistical analysis, such as; frequency, percentage and chi-square test. A p-value < 0.05 was considered statistically significant. Results: The most frequently prescribed antibiotic was ciprofloxacin insert ignore into journalissuearticles values(58, 29%);, followed by nitrofurantoin insert ignore into journalissuearticles values(39, 19.5%); and ceftriaxone insert ignore into journalissuearticles values(32, 16%);. About, 86 insert ignore into journalissuearticles values(43%); patients received an appropriate antibiotic. The dose was given according to the guidelines in 84.5% of patients, whereas the duration of prescribed antibiotic was appropriate in 61% of the patients, with a significant inappropriate dose and duration in pyelonephritis patients. A total of 58 patients were completely correct in all steps insert ignore into journalissuearticles values(drug, dose and duration);. The appropriate prescribing of antibiotic with respect to selection/choice, dose and duration were more in cystitis as compared to pyelonephritis. Conclusions: A low adherence rate with guidelines was observed. Identifying barriers to guideline adherence and urgent steps for the improved prescribing practices in uncomplicated urinary tract infections are required.
Keywords : infection, women, antibiotic, Pakistan, guidelines