Head and neck lymphomas from otolaryngology perspective

Authors : Faruk Kadri BAKKAL, Nagihan GÜLHAN, Fakih Cihat ERAVCI, Yusuf KIZIL, Utku AYDİL

Pages : 675-679

Doi:10.32322/jhsm.948863

View : 23 | Download : 11

Publication Date : 2021-09-05

Article Type : Research Paper

Abstract :Aim: To evaluate the clinical manifestations, histopathologic composition, and demographic characteristics of the lymphomas presented in the head and neck. Materials and Methods: Records of subjects who had a diagnosis of lymphoma by an otolaryngology clinic in a tertiary referral hospital between May 2007 and July 2017 were reviewed. Demographic features and data regarding histopathology, radiology, and clinical presentation were evaluated. Results: A total of 103 lymphomas in the head and neck region, 79 insert ignore into journalissuearticles values(77%); nodal lymphoma, and 24 insert ignore into journalissuearticles values(23%); extranodal lymphoma, were diagnosed. The initial presentation was solitary lymphadenopathy in 12 insert ignore into journalissuearticles values(15%); of the nodal lymphomas but conglomerated or multiple lymphadenopathies in the others. No significant relationship was found between lymph node size and histopathology insert ignore into journalissuearticles values(p=0.144);. Extranodal lymphomas presented most commonly in tonsils insert ignore into journalissuearticles values(n=8, 33%);. Hodgkin lymphoma to non-Hodgkin lymphoma ratio was 0.8 insert ignore into journalissuearticles values(35/44); among nodal lymphomas. The dominant subgroup of non-Hodgkin lymphomas was diffuse large b-cell lymphoma insert ignore into journalissuearticles values(n=18, 40%);. All of the Hodgkin lymphomas in our series were classic variant, and the subjects were younger than the non-Hodgkin lymphomas insert ignore into journalissuearticles values(z=-4.803, p<0.001);. The histopathology of 46 insert ignore into journalissuearticles values(68%); of non-Hodgkin lymphomas was aggressive. T/NK-cell NHL was detected in seven subjects insert ignore into journalissuearticles values(6.8%);. This was the only group with male predominance insert ignore into journalissuearticles values(n=5, 71%);. Conclusion: Lymphomas are a large group of malignancies that can present in various clinical forms in the head and neck region. The gender and age of onset of this neoplasm differ by many biological, environmental, and epidemiological factors. Ultrasound findings are crucial in evaluating suspicious lymph nodes. A tissue biopsy is recommended to exclude lymphomas from other neoplasms to make an accurate diagnosis.
Keywords : Lymphoma, head and neck, malignancy