Pre-hospital antithrombotic drug use status of died COVID-19 patients

Authors : Fatih GÜNEYSU, Ensar DURMUŞ

Pages : 564-568

Doi:10.32322/jhsm.971453

View : 20 | Download : 5

Publication Date : 2021-09-05

Article Type : Research Paper

Abstract :Objectives: In this study, we determine the prehospital antithrombotic drug use rates of patients in Covid-19 mortality to reveal the differences between patients using antithrombotic drugs and those who did not to show whether antithrombotic drugs impact the duration of stay in intensive care. Methods: This retrospective study was conducted with 291 patients admitted to the xxx University Training and Research Hospital emergency department between March 13 and December 1, 2020. Patients whose PCR test was positive and who died in our hospital were included in the study. Results: The median number of days in the intensive care unit of patients using acetylsalicylic acid insert ignore into journalissuearticles values(7; 3-11); was longer than patients who were not using acetylsalicylic acid insert ignore into journalissuearticles values(5; 1-10); insert ignore into journalissuearticles values(p=0.041);. Also, the median days in the intensive care unit of patients who were not using any antithrombotic drug insert ignore into journalissuearticles values(5; 1-10); was shorter than patients who were using an antithrombotic drug insert ignore into journalissuearticles values(7;3-11); insert ignore into journalissuearticles values(p=0.032);. There was no difference in patients using or not using other antithrombotic drugs insert ignore into journalissuearticles values(p=0.640); or acetylsalicylic acid and other antithrombotic drugs insert ignore into journalissuearticles values(p=0.979);. Conclusion: This study shows that the prehospital use of aspirin has a positive effect on survival as it prolongs the length of stay in the intensive care unit. Since it is known that one of the most important causes of death in Covid-19 is hypercoagulopathy and considering the irreversible antiplatelet activity of aspirin and since this activity lasts for up to 10 days, the result seems reasonable.
Keywords : Covid 19, acetylsalicylic acid, prehospital, antithrombotic