Hyperlipidemia in Post-COVID patients; a unique observational follow-up study on lipid levels in post-COVID patients

Authors : Oğuz Abdullah UYAROĞLU, Murat ÖZDEDE, Nursel ÇALIK BAŞARAN, Bahadır KÖYLÜ, Taha Koray SAHİN, Lale ÖZIŞIK, Mine Durusu TANRIÖVER, Gülay Sain GÜVEN

Pages : 220-226

Doi:10.32322/jhsm.1027661

View : 18 | Download : 10

Publication Date : 2022-01-17

Article Type : Research Paper

Abstract :Aim: Alterations in plasma lipid levels have been shown to be correlated with the severity of infections due to various pathogens such as bacteria, viruses. In this study, we aimed to evaluate the lipid metabolism changes associated with disease severity and prognosis in hospitalized COVID-19 patients during and after insert ignore into journalissuearticles values(post-COVID); the disease. Material and Method: Patients who were hospitalized in the COVID-19 wards between April 02, 2020, and November 20, 2020 and were then evaluated in the follow-up outpatient clinic were retrospectively searched. Results:  Lipid levels were present at the admission and follow-up for 95 patients. The mean insert ignore into journalissuearticles values(S.D); age was 48.49 insert ignore into journalissuearticles values(16.4);, and 49insert ignore into journalissuearticles values(51.6%); were male. The mean insert ignore into journalissuearticles values(S.D); day between the admission and the first visit in the COVID-19 follow-up outpatient clinic was 27.8 insert ignore into journalissuearticles values(12.8);. LDL-C insert ignore into journalissuearticles values(p=0.044);, and HDL-C insert ignore into journalissuearticles values(p=0.004); levels were significantly lower in the severely ill group at the admission. Total cholesterol, LDL-C, HDL-C, and triglyceride levels on follow-up were significantly higher than those levels on the admission day insert ignore into journalissuearticles values(p<0.001);. Delta insert ignore into journalissuearticles values(Follow up-Admission); levels LDL-C, total cholesterol and triglyceride levels were significantly high in patients who have received steroid therapy. Only delta LDL-C was significantly high in patients who require Intensive Care Unit. Conclusions: Dyslipidemia is observed in COVID-19 patients both during the disease and in the post-COVID period. Our findings also support the evidence demonstrating that low LDL-C and/or HDL-C levels can increase the risk of developing severe infections, also in COVID-19. The dynamics of lipid profiles before/during and after the entire disease course should be monitorized.
Keywords : COVID 19, dyslipidemia, hyperlipidemia, post COVID, Long COVID