Evaluation of thyroid dysfunctions frequency in the first trimester

Authors : Kazım UÇKAN, İzzet ÇELEĞEN, Yusuf BAŞKIRAN

Pages : 466-470

Doi:10.32322/jhsm.1015213

View : 10 | Download : 7

Publication Date : 2022-03-15

Article Type : Research Paper

Abstract :Aim: The aim of the study is to determine the frequency of first-trimester thyroid dysfunction in pregnant women and to investigate the effect of thyroid dysfunction on some perinatal outcomes. Material and Method: In the study, first-trimester Thyroid stimulating hormone insert ignore into journalissuearticles values(TSH);, free T4 and free T3 hormone values of pregnant women who applied to our outpatient clinic were retrospectively scanned and recorded. As a result, 3224 pregnant women were included in the study. Pregnant women were evaluated as overt hypothyroidism, subclinical hypothyroidism, overt hyperthyroidism, subclinical hyperthyroidism and euthyroid according to TSH and fT4 values. Results of thyroid function tests of pregnant women and some perinatal results insert ignore into journalissuearticles values(age, gestational week, delivery type, baby gender, birth weight, gravida, parity, abortion); were compared Results: In our study, the mean age of the pregnant women for screening was 28.6±3.1, the mean birth week was 38.7±2.1, and the mean birth weight was 3037±324.73.6% insert ignore into journalissuearticles values(n=2369); of the pregnant women were normal euthyroid, 0.71% insert ignore into journalissuearticles values(n=23); were subclinical hyperthyroidism, 0.65% insert ignore into journalissuearticles values(n=23); were overt hyperthyroidism, while 15.6% insert ignore into journalissuearticles values(n=507); were overtly hypothyroid and 9.4% 3 insert ignore into journalissuearticles values(n=304); were found to be subclinical hypothyroidism. A significant statistical difference was not found between thyroid outcome test results and perinatal outcomes insert ignore into journalissuearticles values(age, gravida, parity, abortion, birth strength, gestational age, delivery type, babies); insert ignore into journalissuearticles values(p> 0.05);. Conclusion: In our study, a high prevalence of thyroid disease, especially hypothyroidism, was observed in pregnant women. More studies should be done to evaluate the effect of thyroid functions on pregnancy outcomes.
Keywords : First trimester, Pregnancy, Thyroid dysfunction, TSH, Perinatal outcomes