Diagnostic and prognostic value of the ratio of mean platelet volume to platelet count in acute mesenteric ischemia

Authors : Murat Bulut ÖZKAN, Ramazan TOPCU, Fatih ŞAHİN, Murat Baki YILDIRIM

Pages : 682-688

Doi:10.32322/jhsm.1076082

View : 17 | Download : 11

Publication Date : 2022-03-15

Article Type : Research Paper

Abstract :Introduction: Acute mesenteric ischemia insert ignore into journalissuearticles values(AMI); is a condition in which there is a sudden cessation of blood supply to a particular intestinal segment and consequent cellular damage. Although it has a low incidence of approximately 0.09-0.2% of all emergency surgery admissions, AMI is a severe condition that can cause high early mortality. A direct relationship between an increased mean platelet volume insert ignore into journalissuearticles values(MPV); and acute thrombotic events has been shown in recent years. we aimed to find out whether the diagnosis of mesenteric ischemia and the amount of bowel segment affected by ischemia will guide clinicians preoperatively with these markers Material and Method: A total of 57 cases with bowel resection due to mesenteric ischemia were included in the study. The gender, age, serum platelet insert ignore into journalissuearticles values(PLT);, MPV, white blood cell count insert ignore into journalissuearticles values(WBC);, neutrophil count insert ignore into journalissuearticles values(NEU);, lymphocyte count insert ignore into journalissuearticles values(LYM);, Albumin, CRP, neutrophil-lymphocyte ratio insert ignore into journalissuearticles values(NLR);, MPV/Platelet Count, and CRP-albumin ratio insert ignore into journalissuearticles values(CAR); levels at the time of admission, operation time, length of resected bowel segment, length of hospital stay, presence of necrosis and perforation from pathology reports, and length of bowel segment leading to necrosis were scanned. Results: A moderate insert ignore into journalissuearticles values(moderate); negative correlation was found between the length of resected bowel segment and PLT insert ignore into journalissuearticles values(P<0.001; r=-0.685);. A moderate positive significant correlation was found between resection length and MPV insert ignore into journalissuearticles values(P<0.001; r=0.565);. A high significant positive correlation was found between resection length and MPV/PC insert ignore into journalissuearticles values(P<0.001; r=0.857);. PLT, WBC and MPV/PC values were statistically different between the perforated group and no-perforation group insert ignore into journalissuearticles values(p=0.009, p=0.024, p=0.010);. WBC and MPV/PC values were significantly higher in the perforated group. Conclusion: MPV/PC and PLT value at hospital admission is a reliable and simple predictive factor in determining perforation and the amount of bowel segment affected in patients with acute mesenteric ischemia.
Keywords : acute mesenteric ischemia, bowel necrosis, mean platelet volume, platelet indices