Evaluation of Healthcare-Related Candida Infections That Develop in the Medical Intensive Care Unit

Authors : İsmail DEMİR, Şebnem ÇALIK

Pages : 35-40

View : 11 | Download : 7

Publication Date : 2020-03-31

Article Type : Research Paper

Abstract :Background: The objective of this retrospective study was to evaluate healthcare-related Candida infections and factors related mortality. Materials and Methods: Patients who were followed-up in the Medical intensive care unit insert ignore into journalissuearticles values(ICU); between 2015 and 2018 were retrospectively evaluated. Data were obtained by active surveillance method based on patient and laboratory. Statistical analysis of the data was performed using the SPSS 22 package program. The number, percentage, mean ± standard deviation and chi-square insert ignore into journalissuearticles values(χ²); test were used to analyze the distribution of the data obtained. p <0.05 was considered statistically significant. Results: Fifty-nine insert ignore into journalissuearticles values(5.8%); of the 1018 patients who were followed up and treated in ICU developed Candida infection. The mean age was 73.9 ± 11.5. 39 patients insert ignore into journalissuearticles values(66.1%); with urinary catheter-related urinary tract infection, 12 insert ignore into journalissuearticles values(20.3%); patients with Laboratory Proven Blood Circulation Infection, 6 insert ignore into journalissuearticles values(10.2%); patients Abscess / soft tissue infection and 2 insert ignore into journalissuearticles values(3.4%); patients were diagnosed as Central Venous Catheter-Associated Blood Stream Infection. 36 insert ignore into journalissuearticles values(61%); of Candida species isolated from cultures were C.albicans, 8 insert ignore into journalissuearticles values(13.6%); were C. parapsilosis, 6 insert ignore into journalissuearticles values(10.2%); were C.glabrata, 6 insert ignore into journalissuearticles values(10.2%); were C.. tropicalis, 1 insert ignore into journalissuearticles values(1.7%); in C. Crusei and 2 insert ignore into journalissuearticles values(3.3%); were not identified species. 31 insert ignore into journalissuearticles values(52.5%); of the patients died. Total parenteral nutrition insert ignore into journalissuearticles values(P: 0.026); and mechanical ventilation insert ignore into journalissuearticles values(P: 0.004); were statistically significant. There was no statistically significant difference between candida species and mortality insert ignore into journalissuearticles values(p = 0.086);. Conclusions: Candida infections in ICUs are important causes of mortality. A good description of mortality related factors in Candida infections may lead to a decrease in mortality.
Keywords : intensive care unit, Candida infection, mortality related factors