Investigation of Anti-HBs, HBsAg Positivity in Patients Infected with Hepatitis C Virus.

Authors : Feray Ferda ŞENOL, İlkay BAHÇECİ, Nuray ARSLAN, Özlem AYTAÇ, Pinar ÖNER, Arzu ŞENOL, Zülal AŞCI TORAMAN

Pages : 90-96

View : 14 | Download : 4

Publication Date : 2021-06-30

Article Type : Research Paper

Abstract :ABSTRACT Background: Hepatitis C virus insert ignore into journalissuearticles values(HCV); infection is one of the important health problems in our country and in the world. While there is no effective vaccine against HCV yet in preventing transmission, there is a protective vaccine against Hepatitis B virus insert ignore into journalissuearticles values(HBV);. Therefore, it is recommended that patients infected with hepatitis C should be screened for hepatitis B and vaccines for prophylactic purposes should be administered to non-infected individuals. In this study, it was aimed to detect seronegative individuals by retrospectively detecting hepatitis B surface antigen insert ignore into journalissuearticles values(HBsAg); and hepatitis B surface antibody insert ignore into journalissuearticles values(Anti-HBS); seroprevalence and isolated AntiHBc IgG positivity in outpatient and inpatient HCV-infected patients admitted to our hospital. Material and Method: In this study; Patients diagnosed with chronic hepatitis C who admitted to our hospital between October 2018 and September 2020 were retrospectively analyzed. Patients in whom HBsAg, hepatitis B Anti-HBs and hepatitis B core antibody insert ignore into journalissuearticles values(Anti-HBc IgG); were investigated, which are among the hepatitis B infection markers, were included in the study. Results: The 821 patients of study group, 305 insert ignore into journalissuearticles values(37.15%); were female, 516 patients insert ignore into journalissuearticles values(62.85%); were male and with a mean age of 47 ± 11.5. Accompanying HBsAg was positive in 17 insert ignore into journalissuearticles values(2.07%); patients, Anti-HBs positivity in 231 insert ignore into journalissuearticles values(28.13%); patients, and isolated Anti-HBc Ig G seropositivity in 75 insert ignore into journalissuearticles values(9.13%); patients. Conclusion:HBsAg, Anti-HBs positivity, isolated Anti-HBc IgG seropositivity in patients with chronic HCV were found to be similar to national and national data. In line with these results, it was concluded that every patient diagnosed with HCV should be screened for HBV serology and that seronegative people should be included in the vaccination program in order to prevent the development of HBV coinfection.
Keywords : AntiHBV, HBV, HCV