The severity of COVID-19 infection in children with leukemia

Authors : Ayça KOCA YOZGAT, Melek ISİK, Dilek KAÇAR, Zeliha GUZELKUCUK, Burçin KURTİPEK, Aslı TURGUTOĞLU YILMAZ, Volkan KÖSE, Dilek GÜRLEK, Turan BAYHAN, Özlem ARMAN BİLİR, İkbal OK BOZKAYA, Namık Yaşar ÖZBEK, Hüsniye Neşe YARALI

Pages : 258-262

Doi:10.47582/jompac.1298127

View : 71 | Download : 68

Publication Date : 2023-08-30

Article Type : Research Paper

Abstract :Aims: The coronavirus disease 2019 insert ignore into journalissuearticles values(COVID-19); has been the cause of a global health crisis since the end of 2019. The aim of this study was to evaluate the clinical findings and treatment results of COVID-19 disease in pediatric patients with leukemia. Methods: All the children and adolescents with severe acute respiratory syndrome coronavirus 2 insert ignore into journalissuearticles values(SARS-CoV-2); positive real-time polymerase chain reaction insert ignore into journalissuearticles values(PCR); and the presence of underlying leukemia were included in the study. Results: A total of 44 leukemia patients with COVID-19 infection were included in the study. Their primary diseases were as follows: 36 patients were newly diagnosed with acute lymphoblastic leukemia insert ignore into journalissuearticles values(ALL);, four patients were relapsed ALL, two patients were refractory ALL, and two patients were acute myeloblastic leukemia. The mean age of patients was 104± 62 months. COVID-19 was asymptomatic in 11.4% of patients, mild in 84%, and moderate in 4.5% whereas none of our patients had a severe infection. No severe complications and/or death were observed in our study group. Conclusion: It has been found that the clinical course of COVID-19 is mild in children and adolescents with leukemia and undergoing chemotherapy or immunosuppressive therapy.
Keywords : Çocuk, COVID 19, Lösemi