The role of the TAPSE/PASP ratio in the prediction of paroxysmal atrial fibrillation in patients with acute ischemic stroke

Authors : Tolga ÇAKMAK, Özgen ŞAFAK

Pages : 355-361

Doi:10.47582/jompac.1338419

View : 35 | Download : 44

Publication Date : 2023-08-30

Article Type : Research Paper

Abstract :Aims: Atrial fibrillation insert ignore into journalissuearticles values(AF); remains the most prevalent cause of cardioembolic stroke. Paroxysmal AF insert ignore into journalissuearticles values(PAF); is often difficult to be diagnosed and is sometimes first detected during embolic stroke. Yet, TAPSE and PASP can be easily revealed in routine transthoracic echocardiography insert ignore into journalissuearticles values(TTE);. Then, the TAPSE/PASP ratio is often shown to have prognostic significance in many cardiac disorders. Nevertheless, the insufficient scholarly knowledge of the relationship between this ratio and the development of PAF became the primary motive of the present study. Methods: We carried out this study with 114 patients experiencing acute ischemic stroke without a previous diagnosis of AF. We noted down the patients’ blood parameters and prescribed drugs and calculated TAPSE/PASP ratio relying on their TTE findings. We also recorded the 24-hour heart rhythm findings of each patient through Holter monitoring. After categorizing PAF attacks insert ignore into journalissuearticles values(i.e.,PAF attack was insert ignore into journalissuearticles values(not); observed);, we explored any statistical relationship between the TAPSE/PASP ratio and the presence of PAF. Results: The findings revealed a significant difference between the TAPSE/PASP ratios between the groups with PAF insert ignore into journalissuearticles values(0.62±0.07); and without PAF insert ignore into journalissuearticles values(0.77±0.08);. Moreover, the receiver operating characteristic insert ignore into journalissuearticles values(ROC); curve analysis yielded the TAPSE/PASP ratio to demonstrate a diagnostic value in predicting PAF insert ignore into journalissuearticles values(area under the ROC curve [AUC]=0.89;82.7%; p<0.001);. Besides, the TAPSE/PASP ratio measured <0.67 at admission was found to have 87.1% sensitivity and 82.7% specificity in predicting PAF. Finally, the multivariate analysis showed the TAPSE/PASP ratio to be a significant risk factor for PAF insert ignore into journalissuearticles values(odds ratio [OR]=2.971;95% confidence interval [CI]=1.073-8.959; p=0.000);. Conclusion: Overall, a low TAPSE/PASP ratio insert ignore into journalissuearticles values(<0.67); may be a precursor of the presence of PAF in patients.
Keywords : Akut iskemik inme, TAPSE PASP oranı, Paroksismal Atriyal fibrilasyon