Predictive value of platelet/albumin ratio in coronary slow-flow patients

Authors : Yunus Emre Yavuz, Sefa Tatar, Muzaffer Aslan

Pages : 304-308

View : 33 | Download : 28

Publication Date : 2024-12-23

Article Type : Research Paper

Abstract :Aims:The pathophysiology of coronary slow flow is not yet fully understood, and it is thought to be related to multiple mechanisms such as endothelial dysfunction, microvascular disorder, and atherosclerosis. In this study, we aimed to investigate the predictive value of platelet/albumin ratio (PAR) in coronary slow flow patients (CSF). In addition, we compared it with other current parameters containing albumin. Methods: The study was designed retrospectively. The study population included a review of the medical records of 260 people who underwent coronary angiography from 2020 to 2023. The study groups consisted of 108 patients with coronary slow flow and 101 patients with normal coronary arteries who met the inclusion criteria. Various parameters such as demographic data, Platelet/Albumin Ratio and prognostic nutritional index were compared between these two groups. ROC analysis was performed on these parameters. Results: There was no significant difference between the coronary slow flow and control groups in terms of basic demographic characteristics such as age, gender and smoking, but BMI (p<0.001), LDL (p:0.026) and total cholesterol (p:0.041) ratios were higher in the coronary slow flow group. PAR showed a significant difference between the coronary slow flow group and the control group (p:0.022). Prognostic nutritional index was not significant (p:0.142). ROC curve analysis for the PAR showed a moderate discriminatory ability with an area under the curve (ROC) of 0.592 (95% CI: 0.517-0.667). Conversely, the prognostic nutritional index exhibited limited diagnostic performance with an AUC of 0.441 (95% CI: 0.365-0.522). Conclusion: These findings suggest that easily measurable PAR may be a valuable biomarker in assessing coronary slow flow, especially in resource-limited settings. Not only does PAR demonstrate a discriminatory ability, but it also outperforms other traditional biomarkers like the prognostic nutritional index (PNI) in this specific patient population.
Keywords : Koroner anjiyografi, trombosit, albümin, koroner yavaş akım