Analyzing the efficacy of transforaminal lumbar interbody fusion (TLIF) surgery for degenerative spondylolisthesis based on clinical outcomes and spinopelvic metrics

Authors : Fahri Eryılmaz

Pages : 314-319

View : 24 | Download : 23

Publication Date : 2024-12-23

Article Type : Research Paper

Abstract :Aims: Transforaminal lumbar interbody fusion (TLIF) is an increasingly used approach for treating degenerative spondylolisthesis, but limited data exist regarding its impact on spinopelvic alignment (SA) and related functional outcomes. Methods: 150 patients who underwent TLIF were enrolled and evaluated pre-operatively and post-operatively in this study. Radiographic analysis was used to measure spinopelvic parameters, including lumbar lordosis (LL), pelvic tilt (PT) and sacral slope (SS). Oswestry disability index (ODI) and visual analog scale (VAS) functional outcomes were assessed. Methods statistical analyses included paired t-tests, Pearson correlation coefficients, and multivariate regression for differences in parameters before and after surgery, associations between changes in spinopelvic parameters and functional outcomes, and predictors of greater improvement in the ODI, respectively. Results: Changes in LL, PT and SS from pre- to post-operative day 10, 30-points posterior pelvic plane re-orientation score. Functional output assessments showed improvement in mean ODI (34 to 20) and VAS (6.5 to 3.2) scores (p<0.001). Pre-operative ODI, post-operative change in LL, PT and SS predicted recovery above chance by multivariate regression (p<0.001). Conclusion: TLIF provides correction to SA and functional outcomes, supporting the importance of pre-operative assessment and targeted surgical planning to optimize quality of life at maximum value for each patient. Longer-term recovery and other pertinent outcome variables should be conducted.
Keywords : transforaminal lomber interbody füzyon, interbody füzyon, omurga cerrahisi, spondilolistezis