Synthesis of Guanidines via Reaction of Amines with Carbodiimides in the Presence of Ionic Liquid

Authors : Foad Shaghayeghi Toosi

Pages : 19-26

Doi:10.18596/jotcsa.44903

View : 6 | Download : 4

Publication Date : 2016-01-11

Article Type : Research Paper

Abstract :Different ionic liquids insert ignore into journalissuearticles values(ILs); were synthesized and evaluated for the preparation of substituted guanidines from the reaction of amines and carbodiimides. 1-methylimidazolium tetrafluoroborate [HMIm]BF4 was found to be the best ionic liquid for this reaction. This IL acted as a promoter for the addition of primary and secondary amines to carbodiimides. By this efficient approach, various guanidines were prepared in excellent yields.
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