Chemical reactivity of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl)-2,4-dioxobutanoate towards some nucleophilic reagents

Authors : Hany Hassanin, Magdi A. Ibrahim, Shimaa Badran

Pages : 75-88

Doi:10.18596/jotcsa.11975

View : 7 | Download : 4

Publication Date : 2016-02-08

Article Type : Research Paper

Abstract :Abstract A novel series of heterocyclic systems linked with quinolin-2-one was efficiently synthesized from reaction of ethyl 4-insert ignore into journalissuearticles values(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl); -2,4-dioxobutanoate insert ignore into journalissuearticles values( 1 ); with a variety of nitrogen and/or carbon nucleophiles. A variety of heterocyclic systems such as pyrazoles, pyrimidines, pyrazines, oxazines and triazines containing quinoline moiety were synthesized. Structures of the new synthesized products were deduced on basis of their analytical and spectral data.
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