CSA-Catalyzed Three-component Synthesis of Fused Polycyclic Pyrazolo[4,3-e]pyridines Under Ultrasonic Irradiation and Their Antioxidant Activity

Authors : Emel PELIT

Pages : 631-648

Doi:10.18596/jotcsa.295465

View : 12 | Download : 8

Publication Date : 2017-05-16

Article Type : Research Paper

Abstract :New fused pyrazolo[4,3-e]pyridines were obtained by multi-component reaction of 1,3-dimethyl-1 H -pyrazol-5-amine or 3-phenyl-1 H -pyrazol-5-amine, aromatic aldehydes and indan-1,3-dione in the presence of camphor-10-sulfonic acid insert ignore into journalissuearticles values(CSA); as an effective catalyst under ultrasound promoted conditions. The antioxidant activity of the pyrazolopyridine compounds 4b , 5c , 5e , 7a , 7b and 7c were determined. 
Keywords : Pyrazolopyridines, multi component synthesis, ultrasonic irradiation, camphor 10 sulfonic acid CSA,