NOVEL ANTIMONY(III) HALIDE COMPLEXES WITH SOME N-ALKYL THIOUREAS: SYNTHESIS, CHARACTERIZATION AND STUDY OF THEIR EFFECT UPON THE CATALYTIC OXIDATION OF LINOLEIC ACID TO HYDROPEROXYLINOLEIC ACID BY LIPOXYGENASE

Authors : İbrahim İsmet ÖZTÜRK

Pages : 81-98

Doi:10.18596/jotcsa.31798

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Publication Date : 2017-01-09

Article Type : Research Paper

Abstract :Four novel antimonyinsert ignore into journalissuearticles values(III); compounds insert ignore into journalissuearticles values(SbX 3 ; X = Cl or Br); of thiourea derivatives; N-methylthiourea insert ignore into journalissuearticles values(NMTU);  and N-ethylthiourea insert ignore into journalissuearticles values(NETU); of formulae [SbCl 3 insert ignore into journalissuearticles values(NMTU); 3 ] insert ignore into journalissuearticles values( 1 );, [SbBr 3 insert ignore into journalissuearticles values(NMTU); 3 ] insert ignore into journalissuearticles values( 2 );, [SbCl 3 insert ignore into journalissuearticles values(NETU); 3 ] insert ignore into journalissuearticles values( 3 ); and [SbBr 3 insert ignore into journalissuearticles values(NETU); 3 ] insert ignore into journalissuearticles values( 4 ); were synthesized. These new antimonyinsert ignore into journalissuearticles values(III); halide compounds were characterized by melting point, elemental analysis, molar conductivity, FT-Infrared spectroscopy, FT-Raman spectroscopy, UV-Vis spectroscopy, NMR insert ignore into journalissuearticles values( 1 H and 13 C); spectroscopy and TG-DTA analysis. The reactions of N-methylthiourea insert ignore into journalissuearticles values(NMTU); and N-ethylthiourea insert ignore into journalissuearticles values(NETU); with SbX 3 insert ignore into journalissuearticles values(X = Cl or Br); in a 2:1 ligand/metal rate but unexpectedly products were formed in a 3:1 ligand/metal rate. The compounds are non-electrolytes in solution and spectroscopic data of the compounds are appropriate with six coordinate octahedral geometry by three halide ions and three sulfur atoms from thiourea ligands. N-methythiourea and N-ethylthiourea ligands behave as monodentate in compounds 1 - 4 with the binding through sulfur.  The influence of these compounds 1 – 4 , N-methythiourea and N-ethylthiourea upon the catalytic peroxidation of linoleic acid to hyperoxolinoleic acid by lipoxygenase was kinetically studied. 
Keywords : Antimony III, halide compounds, N alkyl thioureas, Spectroscopic Characterization, Lipoxygenase