Residual Determination of Multiple Pesticides in Vegetable Samples by LC-MS/MS Coupled with Modified QuEChERS-dSPE Ionic Liquid-Based DLLME Method

Authors : Abubakar LAWAL, Kah LOW

Pages : 693-704

Doi:10.18596/jotcsa.845578

View : 13 | Download : 9

Publication Date : 2021-05-31

Article Type : Research Paper

Abstract :As a matter of fact, the Dietary Guidelines of the United States of America recommended the consumption of more fruits and vegetables to support the healthy condition of the body. Unfortunately, these food materials are being accumulated with pesticidal residues due to the continuous miss-management and excessive application of the chemicals during pre and post-agricultural practices, which compels multiple analysis of pesticidal residues to know their concentration levels for the betterment of food security and safety. For that matter, multi-residues of Thiamethoxam, Propamocarb, Carbaryl, Metalaxyl, Baycarb, Thiobencarb, Diazinon, and Dursban pesticides were determined in the samples of lettuce, garlic, ginger, and bell-pepper using modified QuEChERS-dSPE Ionic Liquid-based dispersive liquid-liquid microextraction insert ignore into journalissuearticles values(DLLME); method coupled with LC-MS/MS instrument and validated insert ignore into journalissuearticles values(European Union Guideline);. Resultantly, the accuracy insert ignore into journalissuearticles values(87-127%); and precision insert ignore into journalissuearticles values(0–22%); were mostly within the acceptable range for the former insert ignore into journalissuearticles values(70-120%); and latter insert ignore into journalissuearticles values(≤20%);. Meanwhile, the limit of detections insert ignore into journalissuearticles values(0.01-0.28 µg/kg); and limit of quantitations insert ignore into journalissuearticles values(0.03-0.93 µg/kg); were satisfactory. The concentration range insert ignore into journalissuearticles values(5–400 µg/kg); of calibration curves for the evaluated linearity were linear with coefficient of regressions greater than 0.99. The matrix effects for all the analyzed samples were very weak and less effective insert ignore into journalissuearticles values(≤ -86%);. The range insert ignore into journalissuearticles values(1–25%); for the estimated measurement uncertainties were certifiable and acceptable insert ignore into journalissuearticles values(≤ 50%);. Therefore, the sample preparation method prove effective as validated and useful for the multiple determination of pesticides residues in the analyzed vegetable samples, which are presumably safe for consumption against health issues.
Keywords : Pesticide residues, Fruits and vegetables, QuEChERS dSPE and DLLME Cleanups, Ionic liquid based, Liquid chromatography tandem mass spectrometry