Fabrication and Characterization of Gelatin/Chitosan Hydrogel Membranes

Authors : Thi Sinh VO, Tran Thi Bich Chau VO, Truong Sinh NGUYEN, Tran Trung TİEN

Pages : 1045-1056

Doi:10.18596/jotcsa.942478

View : 10 | Download : 9

Publication Date : 2021-11-30

Article Type : Research Paper

Abstract :The gelatin/chitosan insert ignore into journalissuearticles values(GEL/CTS, GC); membranes have been fabricated well by a simple in-situ method. The as-prepared GC membranes were characterized by morphological surface insert ignore into journalissuearticles values(scanning electron microscopy, SEM);, chemical insert ignore into journalissuearticles values(Fourier-transform infrared spectroscopy, FT-IR);, crystallinity insert ignore into journalissuearticles values(X-ray diffraction, XRD);, thermal insert ignore into journalissuearticles values(thermal gravimetric analysis, TGA);, mechanical insert ignore into journalissuearticles values(tensile test);, hydrophilic insert ignore into journalissuearticles values(water contact angle);, and swelling properties to elucidate the changes in their chemical structures and morphologies. The morphological structure of the GC membranes was found to be very smooth, non-rough and homogeneous. The FT-IR and XRD studies manifest that the GC membranes have good interaction and compatibility between GEL and CTS in the hydrogel mixture. The prepared GC membranes also obtain better thermal, mechanical and swelling properties comparing to the raw CTS molecule. These results suggest that the nontoxic GC membrane can become a preferred hydrogel membrane in the field of wound dressing or tissue-engineering applications.
Keywords : Chitosan, Gelatin, Swelling, Hydrogel Membrane