Multi-criteria decision-making approach in biological risk assessment methodology with bioRAM© program

Authors : Ergün Eraslan, Nuray Alpoğlu Akbulut

Pages : 1801-1823

Doi:10.56554/jtom.1335703

View : 209 | Download : 121

Publication Date : 2023-12-29

Article Type : Research Paper

Abstract :The Multi-Criteria Decision Making approach in risk assessment with the BioRAM © methodology enables comparison of the relative risks posed by biological agents and analysis in the laboratory environment. The questionnaire used in this method is based on the principle of calculating the weights of probability and severity criteria with expert opinions using Saaty\'s semantic pairwise comparison scale. The model, which assigns values between 0 and 1 to the sub-variables of the criteria, is used as a standard scale in biological risk assessment. In the study, biological risk assessment of the process \"Detecting Coagulase positive Staphylococcus aureus in raw milk samples\" was carried out with the BioRAM© 2022 program. According to the program that calculates the criterion weights with 2-dimensional graphics, the risk level through inhalation, contact, and digestion is calculated as high risk according to the biochemical properties of the biological agent. When applying microbiological analysis procedures, it was calculated as high risk through contact and ingestion, medium risk through percutaneous injury, and medium risk through inhalation. It poses a high risk to the public through inhalation, ingestion and contact. The risk level through percutaneous injury is calculated as medium risk. After biosafety and risk reduction measures were taken, the risk level of the analysis was calculated as medium risk through ingestion, contact, and inhalation. However, despite the precautions, the risk level posed by the analysis to society is high through contact, ingestion, and inhalation. Although good precautions were taken, the risk level could not be brought to an acceptable level. At the end of the study, it was recommended to increase Personal Protective Equipment measures to bring the risk level to an acceptable level during the manipulations of this microorganism. In addition, it has been suggested to use molecular techniques that reduce material volume and aerosol risk instead of traditional microbiological analyses in the manipulation of this microorganism.
Keywords : BioRAM©, Olasılık, Şiddet, Çok Kriterli Karar Verme