Serum pentraxin 3 levels in cats with feline parvovirus infection

Authors : Mehmet EROĞLU, Hidayet Metin ERDOĞAN

Pages : 150-158

Doi:10.31797/vetbio.1321720

View : 47 | Download : 44

Publication Date : 2023-08-30

Article Type : Research Paper

Abstract :Feline parvovirus insert ignore into journalissuearticles values(FPV); infection continues to be a serious problem in cats and therefore studies are ongoing to investigate all aspects of the disease. This study was designed to determine the levels of PTX-3 in cats with feline panleukopenia insert ignore into journalissuearticles values(FPL);. Blood samples were taken from 12 cats of different breeds and gender with complaints of weakness, listlessness, anorexia, diarrhoea, vomiting and FPV positive on examination and from 7 cats found healthy on physical and laboratory examination. Whole blood, biochemical parameters, total antioxidant status insert ignore into journalissuearticles values(TAS);, total oxidant status insert ignore into journalissuearticles values(TOS);, oxidative stress index insert ignore into journalissuearticles values(OSi);, serum amyloid A insert ignore into journalissuearticles values(SAA);, C-reactive protein insert ignore into journalissuearticles values(CRP); and pentraxin-3 insert ignore into journalissuearticles values(PTX-3); concentrations were determined in both sick and healthy cats. The results showed that there was marked panleukopenia and serum PTX-3 insert ignore into journalissuearticles values(58.69 pg/mL);, SAA insert ignore into journalissuearticles values(59.91 µg/mL);, TOS insert ignore into journalissuearticles values(14.35 μmol H2O2 Eq/L); and OSi insert ignore into journalissuearticles values(1.17 arbitrary unit); levels were significantly higher in cats diagnosed with FPL compared to healthy subjects. In conclusion, serum PTX- levels were measured for the first time in cats naturally infected with FPV and found to be elevated. Further clinical studies with large numbers of infected cats are needed to clarify these findings and to use PTX-3 as a reliable biomarker in FPV-infected cats.
Keywords : cats, panleukopenia, pentraxin 3, acute phase proteins, oxidative stress