Regression of Q Waves and Clinical Outcomes After Primary Percutaneous Coronary Intervention in St Elevation Myocardial Infarction

Authors : Zeki ŞİMŞEK, Sedat KALKAN, Regayip ZEHİR, Elnur ALİZADE

Pages : 127-131

View : 15 | Download : 3

Publication Date : 2022-08-20

Article Type : Research Paper

Abstract :Introduction: Pathological Q waves are correlated with infarct size, and Q wave regression is associated with left ventricular ejection fraction improvement. There are limited data regarding the association between Q wave regression and clinical outcomes. Our main objective was to assess the association of pathological Q wave evolution after reperfusion with clinical outcomes after ST-elevation myocardial infarction insert ignore into journalissuearticles values(STEMI);. Patients and Methods: Standard 12-lead electrocardiograms insert ignore into journalissuearticles values(ECGs); were recorded in 1553 patients, who presented to our hospital with chest pain and underwent primary percutaneous coronary intervention insert ignore into journalissuearticles values(p-PCI); with the diagnosis of STEMI and were retrospectively analyzed. ECGs were recorded before and 90 min after PCI, as well as at hospitalization discharge and 12 months of follow-up. The study population was divided into three groups as the Q wave regression group, the Q wave persistent group, and the non-Q wave MI group. Results: There were 502 insert ignore into journalissuearticles values(32%); patients with persistent Q waves insert ignore into journalissuearticles values(PQ group);, 509 insert ignore into journalissuearticles values(33%); patients with Q wave regression insert ignore into journalissuearticles values(RQ group);, and 542 insert ignore into journalissuearticles values(35%); patients with non-Q wave MI insert ignore into journalissuearticles values(NQ group);. The degree of LVEF was significantly greater in the RQ group and NQ group than in the PQ group [insert ignore into journalissuearticles values(47.5 ± 10.1 vs. 49.2 ± 9.9); vs. 43.3 ± 10.5 respectively, p< 0.01]. One-year mortality was significantly greater in the PQ group compared to the RQ and NQ groups [19 insert ignore into journalissuearticles values(3.78%); vs. 11 insert ignore into journalissuearticles values(2.16%); vs. 6 insert ignore into journalissuearticles values(1.1%); respectively, p< 0.01]. Conclusion: In a population of STEMI patients, persistent Q waves defined according to the classic ECG criteria after reperfusion were associated with high one-year mortality, and low LVEF, while Q wave regression was associated with significantly lower risk of events.
Keywords : ST elevation myocardial infarction, Q wave regression, primary percutaneous coronary intervention