Complete response with alternative combination chemotherapy in endodermal sinus tumor case of the ovary

Authors : M. Erenus, F. Durmu§oglu Durmuşoğlu

Pages : 41-42

View : 4 | Download : 2

Publication Date : 1992-01-01

Article Type : Research Paper

Abstract :A 20 year old female with endodermal sinus tumor of the ovary, Stage III, underwent cytoreductive surgery and combination chemotherapy at Ankara Maternity Hospital, Ankara, Turkey. The patient was initially treated with Vincristine, Actinomycin and cyclophosphamide. The patient was followed by Alpha-feto- Protein which demonstrated a rise in titer which was then managed by Vinblastine, Bleomycin and CIS- platinum. The patient was documented to be in complete clinical and surgical remission by a `second- look` laparotomy. This is the first patient with an advanced germ cell tumor treated by aggresive surgery and multi-agent chemotherapy in Turkey.
Keywords : chemotherapy, tumor, response