Elemental variations in preeclampsia

Authors : N. ASKAR, C. ÇOKER, H.h. AYDIN, B. ERSÖZ, T. ATEŞ

Pages : 178-182

View : 12 | Download : 4

Publication Date : 1996-10-01

Article Type : Research Paper

Abstract :Objective: There are alterations in elemental metabolism due to physiological and pathological processes in pregnancy. In this study, the physiological distribution of elements between the mother and the fetus is investigated along with the variations in the elemental status of the maternal- fetal-placental unit in pregnancies complicated with preeclamptic toxemia. Methods: Cu. Zn, Fe, Mg and Ca levels in placental tissue, maternal and fetal plasma and fetal red blood cells in the healthy individuals insert ignore into journalissuearticles values(n=9); and preeclamptics insert ignore into journalissuearticles values(n=10); are determined by inductively coupled plasma atomic emission spectrometry. Results: Within the control group, significant differences between maternal and fetal plasma have been detected with respect to Cu insert ignore into journalissuearticles values(p<0.001); and Feinsert ignore into journalissuearticles values(p<0.05); levels. Comparing the preeclamptics with the controls, the most marked variation is observed in Zn status with significantly decreased concentrations in maternal and fetal plasma insert ignore into journalissuearticles values(p<0.05); and fetal red blood cells insert ignore into journalissuearticles values(p<0.01);. Significant variations are also determined for Cu in fetal red blood cells insert ignore into journalissuearticles values(p<0.05);, Ca in placental tissue insert ignore into journalissuearticles values(p<0.01); and fetal plasma insert ignore into journalissuearticles values(p<0.05);. Conclusion: This study points out the disturbances in the elemental status of the maternal-fetal-placental unit in preeclampsia.
Keywords : Pregnancy, Preeclampsia, Placenta, Trace elements, Ca, Mg