FREE FLOW CAPACITY OF INTERNAL THORACIC ARTERY GRAFTS AFTER SODIUM NITROPRUSSIDE INJECTION TO THE PEDICLE

Authors : Cem YORGANCIOĞLU, Hilmi TOKMAKOĞLU, Serdar GÜNAYDIN, Zeki ÇATAV, Kaya SÜZER

Pages : 143-147

View : 15 | Download : 4

Publication Date : 2016-12-03

Article Type : Research Paper

Abstract :Objective: The internal thoracic artery insert ignore into journalissuearticles values(ITA); is currently the preferred conduit for myocardial revascularization; however, perioperative vasospasm of the ITA may cause morbidity. Pedicle preparation and pharmacological vasodilatory treatment vary greatly. This clinical study was performed in order to define the effectiveness of two different applications of sodium nitroprusside as vasodilating agent. Methods: Eighty-six consecutive patients whose left ITA was mobilized only by one surgeon for elective coronary artery bypass graft operations were randomly divided into two groups. The ITA was allowed to bleed freely, and the flow was determined insert ignore into journalissuearticles values(flow 1); in group I insert ignore into journalissuearticles values(n=42); 3 mg sodium nitroprusside in 10 ml of 5% dextrose solution was sprayed with pressure on the pedicle with a thin 25 gauge needle. In group II insert ignore into journalissuearticles values(n=44); half of the solution was sprayed in the same manner, and the other half of the solution was injected into the pedicle in the periarterial tissue along the length of the pedicle. Free flows of the ITA were registered before cardiopulmonary bypass insert ignore into journalissuearticles values(flow 2); and also just prior to performing ITA anastomosis to the left anterior descending artery insert ignore into journalissuearticles values(flow 3);. With each measurement hemodynamic parameters and the time between measurements were recorded. Results: No statistically significant differences were found between the groups in respect to sex ratio, age, body surface area, heart rate 1 and 2, mean arterial pressure 1 and 3. There was no significant difference in the initial flow among groups.Significant differences were noted in the second flow measurement insert ignore into journalissuearticles values(p<0.05); and in the third flow measurement insert ignore into journalissuearticles values(p<0.01); between two groups. For each group there was a significant increase in flow from flow 1 to flow 2 and from flow 2 to flow 3 insert ignore into journalissuearticles values(p<0.02);. Conclusion: Sodium nitroprusside injection to the pedicle provides a better flow than simple spraying of the same agent. Key Words: Sodium nitroprusside, Internal thoracic artery, Vasospasm, Vasodilatation.
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