DISEASE ACTIVITY AND FUNCTIONAL STATUS IN TURKISH PATIENTS WITH RHEUMATOID ARTHRITIS

Authors : Nuray Geçer, Şule YAVUZ, Pamir ATAGÜNDÜZ, Nevsun ARITAN, Haner DİRESKENELİ

Pages : 85-89

View : 9 | Download : 4

Publication Date : 2016-12-03

Article Type : Research Paper

Abstract :Objective: Turkish patients with rheumatoid arthritis insert ignore into journalissuearticles values(RA); followed in a university rheumatology clinic, were evaluated cross- sectionally for clinical, socio-economical and laboratory features, correlations with disease activity insert ignore into journalissuearticles values(DAS); and functional outcome were assessed using a Modified Health Assessment Questionnaire insert ignore into journalissuearticles values(M-HAQ);. Methods: Sixty-five patients with RA insert ignore into journalissuearticles values(F/M: 8/1, mean age: 49.7 + 11,9 years); were investigated. Besides socio-demographic evaluations, patients were analyzed for clinical disease activity, laboratory findings and medication. Univariate and logistic regression analysis of the scores with DAS and M-HAQ were performed. Results: Despite a long disease duration insert ignore into journalissuearticles values(97,0+76,9 months); the functional indices insert ignore into journalissuearticles values(M- HAQ: 0,6+0,6 and ACR: 2,1+0,9); of the patients were limitedly elevated. However, pain visual analog scale insert ignore into journalissuearticles values(VAS: 3,5+2,7);, tender joint score insert ignore into journalissuearticles values(TJS: 8,3+8,3);, swollen joint score insert ignore into journalissuearticles values(SJS: 1,9+3,2);, disease activity score insert ignore into journalissuearticles values(DAS: 3,3+1,3);, deformed joint score insert ignore into journalissuearticles values(DJS: 3,2+5,6); and acute phase responses insert ignore into journalissuearticles values(ESR: 57,8+58,2 mm/h, CRP: 15,9+15,2 mg/dl); were moderately high in our population. DAS was found to correlate with most activity criteria, whereas M-HAQ had a limited correlation. Conclusion: Our results suggest that the average RA patient has a limited disability after a mean of 8 years of disease duration in a Turkish university clinic setting. However, disease activity was not suppressed adequately in most patients. DAS was observed to be a good composite measure of disease activity, in good correlation with most single activity measurements. Key Words: Rheumatoid arthritis, Disease activity scores, Health Assessment Questionnaires
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