Diagnostic accuracy of noncompacted-to-compacted wall ratio criteria on CMRI for the diagnosis of left ventricular noncompaction

Authors : Deniz ALIS, Ahmet Anil SAHIN, Arda GULER, Ozan ASMAKUTLU

Pages : 124-129

Doi:10.5472/marumj.637581

View : 14 | Download : 5

Publication Date : 2019-10-31

Article Type : Research Paper

Abstract :Objectives: To investigate the diagnostic accuracy of the current criterion, noncompacted-to-compacted insert ignore into journalissuearticles values(NC/C); wall ratio > 2.3 on cardiac magnetic resonance imaging insert ignore into journalissuearticles values(CMRI); for the diagnosis of left ventricular noncompaction insert ignore into journalissuearticles values(LVNC);. Materials and Methods: We retrospectively enrolled 37 patients as an LVNC group and a total of 97 participants with ischemic, hypertrophic, and dilated cardiomyopathy and healthy controls as a control group. The NC/C ratio was measured perpendicularly on short-axis cine images for segments 1-16 and four-chamber cine images for the apex during the end-diastole. The sensitivity, specificity, and diagnostic accuracy of NC/C ratio > 2.3 for the diagnosis of LVNC were calculated. Results: LVNC patients comprised 24 males insert ignore into journalissuearticles values(64.8%); and 13 females insert ignore into journalissuearticles values(35.2%); with the mean age of 29.24 ± 11.79 years. The NC/C ratio > 2.3 detected in all but one of the LVNC patients insert ignore into journalissuearticles values(97.3%);. On the other hand, the specificity of NC/C ratio > 2.3 was 79.4% for the diagnosis of the LVNC patients. Using NC/C ratio > 2.66 and > 2.8 yielded 91.9% sensitivity and 97% specificity, and 81% sensitivity and 100% specificity, respectively. Conclusion: NC/C ratio > 2.3 might lead to overdiagnosis of LVNC. We suggest using higher NC/C cut-off value in individuals without high clinical suspicion of LVNC.
Keywords : Accuracy, Cardiomyopathy, CMR, Cut off, Noncompaction