Ultrasound shear-wave elasticity and magnetic resonance diffusion coefficient show strong inverse correlation in small fibroadenomas

Authors : Nurten ANDAC BALTACIOGLU, Derya TURELI

Pages : 24-28

Doi:10.5472/marumj.866519

View : 11 | Download : 5

Publication Date : 2021-01-29

Article Type : Research Paper

Abstract :Objective: Stiffness of breast lesions helps distinguish malignant from benign solid masses. Stiffness can be quantitatively measured by magnetic resonance and ultrasound imaging using apparent diffusion coefficient insert ignore into journalissuearticles values(ADC); and shear-wave elastography insert ignore into journalissuearticles values(SWE); techniques, respectively. This study aims to analyze correlations between SWE and ADC in biopsy-proven small fibroadenomas. Patients and Methods: Shear-wave elastography and ADC measurements of 50 fibroadenomas were evaluated retrospectively. Mean patient age was 41±13 years insert ignore into journalissuearticles values(range 27-63);. All lesions had maximum diameters of ≤20 millimeters. Correlations between intralesional ADC, lesion-parenchyma ADC ratio, intralesional SWE, SWE heterogeneity index and lesion volume were analyzed. Results: Mean values of lesions were as follows: ADC=1.71±0.22 x10-3mm2/s, ADC ratio=1.04±0.09, maximum SWE=73.4±28.8 kPa, minimum SWE=43.9±21.8 kPa and SWE heterogeneity index =29.4±12.7 kPa. There was a strong inverse correlation between fibroadenoma ADC and SWE values insert ignore into journalissuearticles values(rho = – 0.746, p <0.01);. Significant correlations were also found between fibroadenoma volume and ADC insert ignore into journalissuearticles values(rho = – 0.525, p <0.05); and SWE insert ignore into journalissuearticles values(rho = 0.840, p <0.01);. Conclusion: Apparent diffusion coefficient and SWE values show strong inverse correlation in small fibroadenomas. If proven threshold values for lesion characterization are revealed, ultrasonographic SWE and diffusion-weighted MRI have potential to be used interchangeably.
Keywords : Apparent diffusion coefficient, Fibroadenoma of breast, Magnetic resonance imaging, Ultrasound shear wave elastography