Revisiting the former approach: Low-dose dopamine in kidney transplant recipients

Authors : Nurdan SENTURK DURMUS, Arzu VELIOGLU, Hakki ARIKAN, Ebru ASICIOGLU, Cumhur YEGEN, Serhan TUGLULAR

Pages : 95-100

Doi:10.5472/marumj.943134

View : 15 | Download : 4

Publication Date : 2021-05-31

Article Type : Research Paper

Abstract :Objective: We aim to evaluate the effects of low-dose dopamine insert ignore into journalissuearticles values(LDD); infusion insert ignore into journalissuearticles values(0.5 – 2.5 g/kg/min); on hemodynamic status and short-term graft function in kidney transplant recipients. Materials and Methods: Patients who underwent kidney transplantation surgery between January 2007 and December 2016 were included in the study. Demographic and laboratory data, presence of delayed graft function, and the rates of rejection, graft loss, and mortality were recorded. The data were compared between patients with and without LDD treatment. Results: A total of 126 patients were included in the study insert ignore into journalissuearticles values(M/F:50.8%/49.2%; mean age, 38.94 ± 11.8 years);. Ninety-four patients insert ignore into journalissuearticles values(74.6%); received living-donor transplants. Fifty-seven patients underwent LDD infusion in the postoperative period insert ignore into journalissuearticles values(LDD group);, while 69 patients did not receive LDD infusion. Demographic and laboratory data of the patients did not significantly differ between groups. Nineteen patients in the LDD group experienced delayed graft function insert ignore into journalissuearticles values(p=0.039);. However, these patients tended to be older, have a longer dialysis period prior to transplantation, deceased and hypertensive donors. There was no significant difference in renal function at 6 months after transplantation between groups. Conclusion: Although, LDD infusion increases kidney blood flow,
Keywords : Kidney transplantation, Dopamine, Delayed graft function, Rejection