The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome

Authors : Ihsan AYHAN, Sehmus ERTOP

Pages : 59-64

Doi:10.5472/marumj.1244731

View : 11 | Download : 3

Publication Date : 2023-01-31

Article Type : Research Paper

Abstract :Objective: In this study, the relationship between changes in mean platelet volume insert ignore into journalissuearticles values(MPV); and erythrocyte distribution width insert ignore into journalissuearticles values(RDW); with hematological response and survival in patients with myelodysplastic syndrome was investigated. Patients and Methods: Between 1 January 2011 and 31 December 2018, patient characteristics and hemogram results were evaluated during the treatment process among 158 patients diagnosed with myelodysplastic syndrome. Results: The mean age of the patients who were included in the study was 71.53±12.6 years. The MPV percentage change in the 2-year follow-up of the patients with and without hematological response was significant, at 0.022±0.11 insert ignore into journalissuearticles values(2.2%); in those who responded and at 0.069±0.15 insert ignore into journalissuearticles values(6.9%); in those who did not insert ignore into journalissuearticles values(p=0.049);. Throughout the same period, the degree of RDW changes in the patients who died was 13.23±22.97, the degree in those who survived was 2.86±21.42, and the difference between the two groups was statistically significant insert ignore into journalissuearticles values(p=0.006);. Conclusion: In patients diagnosed with myelodysplastic syndrome, MPV and RDW values can be considered inexpensive and simple laboratory markers that can be used in follow-ups and promising tests to predict both treatment response and survival in the early period and change treatment modalities.
Keywords : Myelodysplastic syndrome, Mean platelet volume, Red cell distribution width, Treatment response, Myelodysplastic syndrome, Mean platelet volume, Red cell distribution width, Treatment response